Infographic announcing NMN’s return as a lawful supplement with FDA decision highlights on NAD+ and ageing

NMN Is Back: What the FDA’s Decision Means for Supplements, NAD+, and Healthy Ageing

A Turning Point For Cellular Health

On September 29, 2025, the U.S. Food and Drug Administration (FDA) officially confirmed that Beta‑Nicotinamide Mononucleotide (NMN) is lawful for use in dietary supplements. This reversal comes after nearly three years of legal and industry pressure led by the Natural Products Association (NPA). For consumers, it means renewed access to one of the most researched NAD+ precursors; for brands like LLG+, it signals a clearer path to innovate responsibly in the field of cellular resilience.

Older man holds pill bottle as female doctor with stethoscope explains dosage in a kitchen setting.

Why NMN Matters?

NMN is a direct precursor to NAD+, a molecule every cell needs to:

  • Convert food into usable energy.
  • Repair DNA and reduce cellular damage.
  • Support enzymes like sirtuins, which regulate ageing and stress response.

As NAD+ levels naturally decline with age, interest in NMN has grown as a way to help maintain energy, focus, and recovery. The FDA’s decision doesn’t make NMN a “miracle cure,” but it does validate its place in the supplement category.

Boxing-style graphic of two men facing each other with VS symbol, highlighting rivalry and competition.

The Backstory: FDA vs. NPA

  • Initial Block: The FDA originally argued NMN was excluded from supplements because it had been investigated as a drug.
  • Industry Pushback: The NPA filed a citizen petition, launched a lawsuit, and rallied consumer support.
  • Reversal: Evidence showed NMN was marketed as a supplement as early as 2017, making it lawful under the Dietary Supplement Health and Education Act (DSHEA).
  • Outcome: FDA acknowledged NMN’s supplement status, echoing a similar reversal in 2022 with NAC (N‑acetyl‑L‑cysteine).

This case highlights how advocacy and legal action can shape access to nutritional ingredients.


What This Means For Consumers

  • More Choice: NMN products can return to shelves and e‑commerce platforms.
  • Greater Clarity: The ruling reduces confusion about legality and availability.
  • Balanced Expectations: NMN supports NAD+ pathways, but results depend on lifestyle factors like sleep, diet, and stress management.


LLG+ Perspective: Science With Responsibility

At LLG+, we see this decision as an opportunity to strengthen our mission:

  • Evidence‑led Formulas: Combining NMN with cofactors (B‑vitamins, minerals) and antioxidants to support the full NAD+ cycle.
  • Absorption‑first Design: Nutrients in forms your body can use efficiently.
  • Transparency: Third‑party testing and clear labeling so you know exactly what you’re taking.

Our goal isn’t just to restore NAD+ but to create synergy—helping sirtuins, mitochondria, and repair systems work together for long‑term resilience.

 

Two children in masks hold potted plants at a table with microscope, notebook, and science tools.


Key Takeaway

The FDA’s recognition of NMN as a lawful supplement is more than a regulatory win; it’s a milestone for nutritional science and consumer choice. For individuals, it means access to a promising tool for cellular health. For brands like LLG+, it reinforces the importance of pairing cutting‑edge science with responsible, transparent product design.

Healthy ageing isn’t about shortcuts—it’s about giving your cells the right tools to perform as they’re meant to. NMN, alongside smart lifestyle habits, is one of those tools.

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